Osteosarcoma exocytosis of soluble LGALS3BP mediates macrophages toward a tumoricidal phenotype
Jing Li, Chenguang Zhao, Yuhuan Li, Junxiang Wen, Shuang Wang, Difan Wang, Hui Dong, Dong Wang, Yonglin Zhao, Xiaohui Wang, Xijing He, Jie Qin
Topics & Concepts
OsteosarcomaCancer researchApoptosisMacrophageTumor microenvironmentSecretionPhenotypeGene silencingProtein kinase BIn vivoCell cultureCell biologyChemistryIn vitroPhosphorylationBiologyTumor cellsBiochemistryBiotechnologyGeneticsGeneImmune cells in cancerImmunotherapy and Immune ResponsesExtracellular vesicles in disease