The phytochemical and chemotaxonomic study of Salvia spp. growing in Ukraine
Oleh Коshovyi, Aіn Raal, А. М. Ковалева, Mykhailo Myha, Тetiana Ilina, Natalia Borodina, А. Н. Комиссаренко, S Illuminata, S Nemorosa, S Pendula, S Sylvestris, S Grandiflora, S Cernua, S Pratensis, S Officinalis, S Scabiosifolia, S Glutinosa, S Aethiopis, S Stepposa, S Sibthorpii, S Nutans, S Austriaca, S Verticillata, S Jash, D Gorai, R Roy, Salvia, O Koshovyi, G Janicsak, I Zupko, I Mathe, J Hohmann, O Firuzi, R Miri, M Asadollahi, S Eslami, A Jassbi, Y Li, C Duan, J Liu, Y Xu, M Eidi, A Eidi, H Zamanizadeh, M Eidi, A Eidi, M Bahar, N Tildesley, D Kennedy, E Perry, E Perry, K Ballard, K Wesnes, S Akhondzadeh, M Noroozian, M Mohammadi, S Ohadinia, A Jamshidi, M Khani, S Akhondzadeh, S Abbasi, O Koshevoi, O Koshovyi, G Zaycev, A Kovalyova, A Komissarenko, O Koshovyi, G Vovk, E Akhmedov, A Komissarenko, A Jassbi, S Zare, O Firuzi, Xiao, K Valant-Vetschera, J Roitman, E Wollenweber, M Wink, K Liu, A Abdullah, M Huang, T Nishioka, L Akang, Azian Azamimi, A, M Holeman, M Berrada, J Bellakldar, A Lildrissi, R Pinel, S Aucheri, S Verbenaca, S Phlomoides, S Argentea, Coassini Lokar, L Moneghini, M, F Salimpour, A Mazooji, S Darzikolaei
Abstract
Salvia officinalis is a well-studied and popular medicinal plant containing toxic thujones, rather limited phytochemical and pharmacological studies have been performed on other Salvia spp. The aim of the study was to perform phytochemical and chemotaxonomic studies of Salvia genus species (n = 16) from Ukraine to identify the most promising species for the pharmaceutical industry. The content of essential oils from the leaves of 16 Salvia spp. has been studied by gas chromatography/mass spectrometry (MS) and polyphenols by high performance liquid chromatography/MS, and a chemotaxonomic study has been performed by calculation of coefficients of occurrence, originality, and pair affinity. The Salvia spp. is characterized by the presence of monoterpenoids, hydroxycinnamic acids -derivatives of caffeic acid, and flavonoids -derivatives of luteolin and apigenin. The highest content of essential oil is observed in the leaves of S. officinalis, S. grandiflora, and S. scabiosifolia (1.41%-1.85%). The highest amount of hydroxycinnamic acids is in the leaves of S. pratensis, S. illuminata, S. austriaca, and S. verticillata; the highest content of flavonoids and phenolic compounds is found in the leaves of S. grandiflora, S. pratensis,