Unipolar Peptidoglycan Synthesis in the <i>Rhizobiales</i> Requires an Essential Class A Penicillin-Binding Protein
Michelle A. Williams, Alena Aliashkevich, Elizaveta Krol, Erkin Kuru, Jacob M. Bouchier, Jonathan Rittichier, Yves V. Brun, Michael S. VanNieuwenhze, Anke Becker, Felipe Cava, Pamela Brown
Abstract
While the structure and function of the bacterial cell wall are well conserved, the mechanisms responsible for cell wall biosynthesis during elongation are variable. It is increasingly clear that rod-shaped bacteria use a diverse array of growth strategies with distinct spatial zones of cell wall biosynthesis, including lateral elongation, unipolar growth, bipolar elongation, and medial elongation.
Topics & Concepts
PeptidoglycanPenicillin binding proteinsComputational biologyBacterial proteinChemistryMicrobiologyClass (philosophy)BiologyCell biologyBacteriaPenicillinBiochemistryComputer scienceAntibioticsCell wallGeneticsArtificial intelligenceLegume Nitrogen Fixing SymbiosisCarbohydrate Chemistry and SynthesisMicrobial Metabolites in Food Biotechnology