Integrin intra-heterodimer affinity inversely correlates with integrin activatability
Guangyu Sun, Emilie Guillon, Scott A. Holley
Abstract
). These observations suggest that a weak integrin intra-heterodimer affinity decreases integrin cell surface stability and increases integrin activatability.
Topics & Concepts
IntegrinFörster resonance energy transferFibronectinCollagen receptorCD49cIntegrin, beta 6Cell biologyChemistryBiophysicsCell adhesionIntegrin alpha MVitronectinCell adhesion moleculeExtracellular matrixReceptorCellBiologyBiochemistryFluorescenceQuantum mechanicsPhysicsCell Adhesion Molecules ResearchCellular Mechanics and InteractionsImmune Response and Inflammation