Litcius/Paper detail

Sequential class switching generates antigen-specific gut IgA from IgG1 B cells

Emily R. Siniscalco, Hailong Meng, Gisela Gabernet, Gaspar A. Pacheco, Shahab Saghaei, Sydney I. Ramirez, L. Benjamin Hills, Farhoud Faraji, Shuting Chen, Xiangyun Yin, Christine Dien, Laura R. Hoyt, Elise G. Liu, Abel Barrett, Neima Briggs, Adam Williams, Vipul Shukla, Shane Crotty, Duane R. Wesemann, Steven H. Kleinstein, Joe Craft, Stephanie C. Eisenbarth

2025Immunity10 citationsDOIOpen Access PDF

Topics & Concepts

Germinal centerImmunoglobulin class switchingBiologyIsotypeImmunologyAntibodyImmunoglobulin AHumoral immunityB cellImmune systemPeyer's patchGut-associated lymphoid tissueLymphatic systemMucosal immunologyImmunoglobulin GImmunityMucosal immunityMicrofold cellMemory B cellImmunoglobulin MTranscytosisImmunoglobulin EIntestinal mucosaAffinity maturationMonoclonal and Polyclonal Antibodies ResearchT-cell and B-cell ImmunologyTransgenic Plants and Applications