Activation of alpha-7 nicotinic acetylcholine receptor by tropisetron mitigates 3-nitropropionic acid-induced Huntington's disease in rats: Role of PI3K/Akt and JAK2/NF-κB signaling pathways
Mostafa A. Rabie, Ahmed T. Ghoneim, Mohamed I. Fahmy, Mohammed F. El-Yamany, Rabab H. Sayed
Topics & Concepts
TropisetronMethyllycaconitinePharmacologyNeuroprotectionProtein kinase BPI3K/AKT/mTOR pathwayStriatumChemistryAntagonistMedicineNicotinic acetylcholine receptorEndocrinologyReceptorInternal medicineNicotinic agonistSignal transductionBiochemistryDopamineGenetic Neurodegenerative DiseasesNicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research