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Managing neonatal hyperbilirubinemia

Andrew Parke Chastain, Anne L Geary, Kevin M Bogenschutz

2024JAAPA16 citationsDOI

Abstract

ABSTRACT: More than 80% of newborn infants experience jaundice as a result of elevated bilirubin during the first few weeks after birth. In most cases, hyperbilirubinemia is physiologic, but persistent and extreme elevations can lead to serious long-term complications, such as kernicterus. To avoid these complications and help clinicians in the successful assessment, evaluation, and treatment of hyperbilirubinemia, the American Academy of Pediatrics updated its clinical practice guideline for neonatal hyperbilirubinemia. This article reviews the guideline and highlights significant updates, such as an elevation in the threshold for phototherapy and exchange transfusion, inclusion of gestational age, and removal of racially based norms.

Topics & Concepts

KernicterusGuidelineMedicineExchange transfusionJaundicePediatricsGestational ageClinical PracticeIntensive care medicinePregnancyInternal medicineFamily medicineGeneticsBiologyPathologyNeonatal Health and BiochemistryMethemoglobinemia and Tumor Lysis SyndromeHemoglobinopathies and Related Disorders
Managing neonatal hyperbilirubinemia | Litcius