Emerging Mechanisms of G <sub>1</sub> /S Cell Cycle Control by Human and Mouse Cytomegaloviruses
Boris Bogdanow, Quang Vinh Phan, Lüder Wiebusch
Abstract
Cytomegaloviruses (CMVs) are among the largest pathogenic viruses in mammals. To enable replication of their long double-stranded DNA genomes, CMVs induce profound changes in cell cycle regulation.
Topics & Concepts
BiologyCell cycleSAMHD1E2FDNA replicationGeneticsGeneCell divisionUbiquitin ligaseViral replicationCell biologyEffectorCellComputational biologyUbiquitinReverse transcriptaseCell cultureRNACytomegalovirus and herpesvirus researchHIV Research and TreatmentImmune Cell Function and Interaction