Fluorosulfonyl Arylation of Alkynes via Electron Donor–Acceptor Photoactivation
Haoyuan Cheng, Tianyu He, Dengfeng Chen, Yu Zheng, Yanju Lu, Hui Liang, Saihu Liao, Shenlin Huang
Abstract
radical precursor via electron donor-acceptor photoactivation driven by daylight or a blue light-emitting diode is disclosed. A series of valuable benzo-fused carbocycles and heterocycles have been produced with simple operation under mild conditions in the absence of any external catalysts or additives. The synthetic potential of this protocol has further demonstrated excellent scalability, as well as diverse postderivatizations, including SuFEx reactions and other useful cascade reactions.
Topics & Concepts
ChemistryCombinatorial chemistryPhotochemistryCatalysisAcceptorElectron acceptorCascadeElectron donorPhotoredox catalysisOrganic chemistryPhotocatalysisCondensed matter physicsChromatographyPhysicsSulfur-Based Synthesis TechniquesRadical Photochemical ReactionsFluorine in Organic Chemistry