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Insights into the design of inhibitors of the EGFR family with anticancer activity overcoming resistance: A case of optimizing thieno[2,3-d]pyrimidine-based EGFR inhibitors

Sandra N. Milik, Amal Kamal Abdel‐Aziz, Morad M. El‐Hendawy, Riham I. El-Gogary, Mona Kamal Saadeldin, Saverio Minucci, Christian D. Klein, Khaled A. M. Abouzid

2022Journal of Molecular Structure10 citationsDOI

Topics & Concepts

T790MEGFR inhibitorsLapatinibChemistryEpidermal growth factor receptorCancerGefitinibCancer researchLung cancerCancer cellBreast cancerBiochemistryReceptorTrastuzumabOncologyMedicineInternal medicineCancer therapeutics and mechanismsHER2/EGFR in Cancer ResearchLung Cancer Treatments and Mutations
Insights into the design of inhibitors of the EGFR family with anticancer activity overcoming resistance: A case of optimizing thieno[2,3-d]pyrimidine-based EGFR inhibitors | Litcius