An expeditious FeCl<sub>3</sub>-catalyzed cascade 1,4-conjugate addition/annulation/1,5-H shift sequence for modular access of all-pyrano-moiety-substituted chromenes
Xinwei He, Ruxue Li, Pui Ying Choy, Jiahui Duan, Zhenzhen Yin, Keke Xu, Qiang Tang, Rong‐Lin Zhong, Yongjia Shang, Fuk Yee Kwong
Abstract
, and particularly under undried acetonitrile and air atmosphere conditions. This method exhibits a broad substrate scope and displays nice functional group compatibility, thus providing an efficient access of 3,4-disubstituted iminochromenes.
Topics & Concepts
SynthonAnnulationAromatizationChemistryMoietyRegioselectivityCombinatorial chemistryCatalysisCycloadditionConjugateAcetonitrileArylMedicinal chemistryStereochemistryOrganic chemistryMathematicsAlkylMathematical analysisSynthesis of Indole DerivativesCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques