Discovery of 8-Hydroxyquinoline as a Histamine Receptor 2 Blocker Scaffold
Paola L. Marquez-Gomez, Nicholas S. Kruyer, Sara L. Eisen, Lily R. Torp, Rebecca L. Howie, Elizabeth V. Jones, Stefan France, Pamela Peralta‐Yahya
Abstract
blocker scaffold, and provides further evidence that antimicrobials not only target the human microbiota but also the human host.
Topics & Concepts
HistamineChemistryPharmacologyReceptorDocking (animal)Drug discoveryScaffoldBiochemistryBiologyMedicineBiomedical engineeringNursingReceptor Mechanisms and SignalingChemical Synthesis and AnalysisAntimicrobial Peptides and Activities