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Gene therapy for primary mitochondrial diseases: experimental advances and clinical challenges

Micol Falabella, Michal Minczuk, Michael G. Hanna, Carlo Viscomi, Robert D. S. Pitceathly

2022Nature Reviews Neurology40 citationsDOI

Topics & Concepts

Mitochondrial DNAGenetic enhancementGenome editingClinical trialMitochondrial diseaseDiseaseBiologyMedicineBioinformaticsComputational biologyGenomeGeneGeneticsPathologyMitochondrial Function and PathologyCRISPR and Genetic EngineeringMetabolism and Genetic Disorders
Gene therapy for primary mitochondrial diseases: experimental advances and clinical challenges | Litcius