Exhaustion of CD39-Expressing CD8+ T Cells in Crohn’s Disease Is Linked to Clinical Outcome
Anna-Maria Globig, L Mayer, Maximilian Heeg, Geoffroy Andrieux, Manching Ku, Patricia Otto-Mora, Anna Hipp, Katharina Zoldan, Ajinkya Pattekar, Nisha Rana, Christoph Schell, Melanie Boerries, Maike Hofmann, Christoph Neumann‐Haefelin, Armin Kuellmer, Arthur Schmidt, Tobias Boettler, Vesselin T. Tomov, Robert Thimme, Peter Hasselblatt, Bertram Bengsch
Topics & Concepts
CD8ImmunologyCrohn's diseaseImmune systemT cellBiologyCytokineFlow cytometryCytotoxic T cellTranscriptomeDiseaseInternal medicineMedicineGene expressionIn vitroGeneGeneticsInflammatory Bowel DiseaseSingle-cell and spatial transcriptomicsCancer Immunotherapy and Biomarkers