Exploring the binding mechanism and adverse toxic effects of degradation metabolites of pyrethroid insecticides to human serum albumin: Multi-spectroscopy, calorimetric and molecular docking approaches
Yiwen Cui, Yingying Sun, Hang Yu, Yahui Guo, Weirong Yao, Yunfei Xie, Fangwei Yang
Topics & Concepts
ChemistryIsothermal titration calorimetryHuman serum albuminCircular dichroismvan der Waals forceDocking (animal)Hydrogen bondQuenching (fluorescence)MetabolitePyrethroidBinding constantStereochemistryFluorescenceBinding siteBiochemistryOrganic chemistryMoleculePesticideBiologyAgronomyPhysicsNursingMedicineQuantum mechanicsProtein Interaction Studies and Fluorescence AnalysisDrug Transport and Resistance MechanismsAntibiotics Pharmacokinetics and Efficacy