Effect of mechanochemical grinding conditions on the formation of pharmaceutical cocrystals and co-amorphous solid forms of ketoconazole – Dicarboxylic acid

Md Sadeque Hossain Mithu, Steven A. Ross, Andrew P. Hurt, Dennis Douroumis

2021Journal of Drug Delivery Science and Technology36 citationsDOI

Topics & Concepts

CocrystalGrindingDissolutionAmorphous solidFumaric acidMaterials scienceSuccinic acidMechanochemistryChemical engineeringOrganic chemistryChemistryMetallurgyNanotechnologyMoleculeHydrogen bondEngineeringCrystallography and molecular interactionsCrystallization and Solubility StudiesPhenothiazines and Benzothiazines Synthesis and Activities