Follicular fluid derived exosomal miR-4449 regulates cell proliferation and oxidative stress by targeting KEAP1 in human granulosa cell lines KGN and COV434
Min Wang, Yixuan Sun, Dong Yuan, Song Yue, Zhu Yang
Topics & Concepts
Polycystic ovaryFollicular fluidOxidative stressKEAP1MicrovesiclesBiologyGranulosa cellOvaryCell growthFollicular phaseInternal medicineEndocrinologySignal transductionCell biologyCancer researchmicroRNABiochemistryMedicineGeneInsulin resistanceOocyteTranscription factorInsulinEmbryoOvarian function and disordersReproductive System and Pregnancy