Reprogramming activated hepatic stellate cells by siRNA-loaded nanocarriers reverses liver fibrosis in mice
Mahmoud A. Younis, Yusuke Sato, Yaser Hosny Ali Elewa, Hideyoshi Harashima
Topics & Concepts
Hepatic stellate cellNanocarriersGene knockdownChemistryIn vivoCancer researchPharmacologyCell biologySmall interfering RNAReprogrammingHepatic fibrosisFibrosisDrug deliveryMedicineBiologyBiochemistryRNAPathologyApoptosisCellOrganic chemistryBiotechnologyGeneLiver physiology and pathologyOrgan Transplantation Techniques and OutcomesLiver Disease Diagnosis and Treatment