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Medical diagnosis of COVID-19 using blood tests and machine learning

Krishnaraj Chadaga, Srikanth Prabhu, Vivekananda Bhat K, Shashikiran Umakanth, Niranjana Sampathila

2022Journal of Physics Conference Series21 citationsDOIOpen Access PDF

Abstract

Abstract Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV-2), colloquially known as Coronavirus surfaced in late 2019 and is an extremely dangerous disease. RT-PCR (Reverse transcription Polymerase Chain Reaction) tests are extensively used in COVID-19 diagnosis. However, they are prone to a lot of false negatives and erroneous results. Hence, alternate methods are being researched and discovered for the detection of this infectious disease. We diagnose and forecast COVID-19 with the help of routine blood tests and Artificial Intelligence in this paper. The COVID-19 patient dataset was obtained from Israelita Albert Einstein Hospital, Brazil. Logistic regression, random forest, k nearest neighbours and Xgboost were the classifiers used for prediction. Since the dataset was extremely unbalanced, a technique called SMOTE was used to perform oversampling. Random forest obtained optimal results with an accuracy of 92%. The most important parameters according to the study were leukocytes, eosinophils, platelets and monocytes. This preliminary COVID-19 detection can be utilised in conjunction with RT-PCR testing to improve sensitivity, as well as in further pandemic outbreaks.

Topics & Concepts

Coronavirus disease 2019 (COVID-19)Random forestOutbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Logistic regressionCoronavirusVirologyPandemicInfectious disease (medical specialty)2019-20 coronavirus outbreakArtificial intelligenceEmerging infectious diseaseOversamplingMedicineComputer scienceReverse transcription polymerase chain reactionMachine learningDiseaseStatisticsInternal medicineBiologyMathematicsGeneBandwidth (computing)Computer networkMessenger RNABiochemistryCOVID-19 diagnosis using AISARS-CoV-2 detection and testingCOVID-19 Clinical Research Studies
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