Litcius/Paper detail

Copper‐Photoredox‐Catalyzed C(sp <sup>3</sup> )–C(sp <sup>3</sup> ) Reductive Cross‐Coupling of Alkyl Bromides with BCP‐Thianthrenium Reagents

Saikat Pandit, Tobias Ritter

2025Angewandte Chemie International Edition12 citationsDOIOpen Access PDF

Abstract

Herein, we report a reductive cross-coupling reaction of bicyclo[1.1.1]pentyl (BCP)-thianthrenium reagents and alkyl bromides. The reaction is catalyzed by a copper/photoredox catalyst system. The approach is the first example of a cross-coupling between BCP-based reagents with alkyl electrophiles.

Topics & Concepts

ReagentAlkylChemistryElectrophileCatalysisCopperCoupling (piping)Coupling reactionCombinatorial chemistryOrganic chemistryMedicinal chemistryPhotochemistryMaterials scienceMetallurgyCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsSulfur-Based Synthesis Techniques