Structure of the SHOC2–MRAS–PP1C complex provides insights into RAF activation and Noonan syndrome
Daniel A. Bonsor, Patrick Alexander, Kelly Snead, Nicole Hartig, Matthew Drew, Simon Messing, Lorenzo I. Finci, Dwight V. Nissley, Frank McCormick, Dominic Esposito, Pablo Rodriguez‐Viciana, Andrew G. Stephen, Dhirendra K. Simanshu
Topics & Concepts
MRASNoonan syndromeBiologyCancer researchGeneticsPhysicsQuantum mechanicsInduction motorVector controlVoltageProtein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase SignalingMicrotubule and mitosis dynamics