RAS–RAF–MEK-dependent oxidative cell death involving voltage-dependent anion channels
Nicholas Yagoda, Moritz von Rechenberg, Elma Zaganjor, Andras J. Bauer, Wan Seok Yang, Daniel J. Fridman, Adam J. Wolpaw, Inese Smukste, John M. Peltier, J. Jay Boniface, Richard A. Smith, Stephen L. Lessnick, Sudhir Sahasrabudhe, Brent R. Stockwell
Topics & Concepts
Voltage-dependent anion channelVDAC1Gene knockdownCell biologyProgrammed cell deathCancer cellSynthetic lethalityKRASMitochondrionApoptosisBiologyChemistryCancer researchBiochemistryCancerMutationBacterial outer membraneGeneticsDNA repairGeneEscherichia coliNeuroscience and Neuropharmacology ResearchMelanoma and MAPK PathwaysRetinal Development and Disorders