Engineering a natural ligand-based CAR: directed evolution of the stress-receptor NKp30
Savannah E. Butler, Rachel A. Brog, Cheryl Chang, Charles L. Sentman, Yina H. Huang, Margaret E. Ackerman
Topics & Concepts
Chimeric antigen receptorFusion proteinReceptorExtracellularCD28Ligand (biochemistry)BiologyIntracellularImmunotherapyCell biologyComputational biologyRecombinant DNAChemistryAntigenMolecular biologyBiochemistryGeneticsGeneImmune systemCD8CAR-T cell therapy researchImmune Cell Function and InteractionNanowire Synthesis and Applications