A plant pentatricopeptide repeat protein with a DYW-deaminase domain is sufficient for catalyzing C-to-U RNA editing in vitro
Michael L. Hayes, Paola I. Santibanez
Abstract
, suggesting that PPR65 cannot bind modified bases due to differences in the structure of the active site compared with other zinc-dependent nucleotide deaminases.
Topics & Concepts
Pentatricopeptide repeatRNA editingIn vitroRNABiologyBiochemistryRNA-binding proteinChemistryCell biologyComputational biologyGeneticsGenePhotosynthetic Processes and MechanismsCRISPR and Genetic EngineeringRNA regulation and disease