Low preoperative serum ALB level is independently associated with poor overall survival in endometrial cancer patients
Jia Lei, Yue Wang, Xiangqian Guo, Shuping Yan, Dimeng Ma, Pengran Wang, Bijun Li, Wenjun Du, Ruixia Guo, Quancheng Kan
Abstract
Aim: To reveal the prognostic significance of serum albumin (ALB) concentration in endometrial cancer (EC) patients in China. Patients & methods: 345 EC patients were enrolled in a single center, and the preoperative serum ALB concentration were measured. Kaplan–Meier curve analysis and Cox proportional hazards regression model were performed to evaluate the associations between ALB concentration and overall survival (OS) of EC patients. Results: The EC patients with lower preoperative serum ALB concentration exhibited a significantly poorer OS (p < 0.05). Univariate analysis and multivariate analysis indicated that serum ALB concentration was an independent prognostic factor of unfavorable OS for EC patients. Conclusion: Our results showing that ALB concentration may serve as an independent prognostic factor for EC patients.