A preliminary study of microwave ablation for solitary T1N0M0 papillary thyroid carcinoma with capsular invasion
Jie Wu, Ying Wei, Zhenlong Zhao, Li-Li Peng, Yan Li, Nai-Cong Lu, Ming-An Yu
Abstract
OBJECTIVE: To evaluate the feasibility, efficiency, and safety of microwave ablation (MWA) for T1N0M0 papillary thyroid carcinoma (PTC) with capsular invasion (CI). METHODS: The data of 69 T1N0M0 PTC with CI underwent MWA from August 2015 to January 2020 were retrospectively analyzed. All PTC nodules were pathologically confirmed by fine needle aspiration (FNA). The extended ablation was performed in all cases, that is, the ablation zone completely covered the tumor and extended the tumor edge by at least 2 mm. The strategy of fluid isolation was successfully applied before and during ablation. The strategy of multiple point ablation was applied. After ablation, the changes in tumor size at different time points, local recurrence, new lesions, lymph node metastasis (LNM), and complications were evaluated and recorded. The technical feasibility, technical success rate, and safety were analyzed. RESULTS: < 0.05 for all). CONCLUSIONS: MWA is an effective, safe, and feasible method in treating T1N0M0 PTC with CI.