Antiradical Activity of Dopamine, L-DOPA, Adrenaline, and Noradrenaline in Water/Methanol and in Liposomal Systems
Katarzyna Jodko-Piórecka, Bożena Sikora, Monika Kluzek, Paweł Przybylski, Grzegorz Litwinienko
Abstract
. Our results from a homogeneous system and bilayers prove that catecholamines act as effective, radical trapping antioxidants with activity depending on the ionization status of the catechol moiety, as well as microenvironment: organization of the lipid system (emulsions vs bilayers) and interactions of catecholamines with the biomembrane.
Topics & Concepts
DopamineLiposomeMethanolEpinephrineChemistryCatecholamineAnesthesiaMedicineInternal medicineBiochemistryOrganic chemistryFree Radicals and AntioxidantsBiochemical effects in animalsBiochemical Acid Research Studies