A bimetallic (Ni/Co) metal–organic framework with excellent oxidase-like activity for colorimetric sensing of ascorbic acid
Jing Wan, Jianmei Zou, Shujing Zhou, Fenglan Pan, Hua Fei, Yulan Zhang, Yu-Lan Zhang, Jin-Fang Nie, Yun Zhang, Yun Zhang
Abstract
. The mechanisms and kinetics of this nanozyme activity were investigated, and it was determined that the catalytic activity of Ni/Co-MOF was closely related to temperature and solution pH. Owing to its strong reducibility, ascorbic acid (AA) could reduce oxTMB, and the blue color of the reaction mixture faded over time. Therefore, a novel colorimetric platform was constructed to detect AA based on the oxidase-like activity of Ni/Co-MOF. Under optimal conditions, the absorbance of ox-TMB at 652 nm decreased linearly over the 0.015-50 μM AA range with a detection limit of 0.004 μM.
Topics & Concepts
Bimetallic stripAscorbic acidChemistryMetalVitamin CInorganic chemistryNuclear chemistryOrganic chemistryBiochemistryFood scienceAdvanced Nanomaterials in CatalysisElectrochemical sensors and biosensorsAdvanced biosensing and bioanalysis techniques