The spatial and single-cell analysis reveals remodeled immune microenvironment induced by synthetic oncolytic adenovirus treatment
Gan Liu, Qifan Hu, Shuguang Peng, Hui Ning, Jiajia Mai, Xi Chen, Minzhen Tao, Qiang Liu, Huiya Huang, Yun Jiang, Yanhua Ding, Xuegong Zhang, Jin Gu, Zhen Xie
Topics & Concepts
Oncolytic virusTumor microenvironmentImmune systemCancer researchBiologyCD8Cancer cellStromal cellCytotoxic T cellOncolytic adenovirusCXCL9CancerImmunologyMedicineChemokineChemokine receptorIn vitroGeneticsBiochemistryVirus-based gene therapy researchCAR-T cell therapy researchImmunotherapy and Immune Responses