Antidiabetic and Cytotoxic Activities of Rotenoids and Isoflavonoids Isolated from <i>Millettia pachycarpa</i> Benth
Virayu Suthiphasilp, Narawadee Rujanapun, Pakit Kumboonma, Boonyanoot Chaiyosang, Sarawut Tontapha, Tharakorn Maneerat, Brian O. Patrick, Raymond J. Andersen, Thidarat Duangyod, Rawiwan Charoensup, Surat Laphookhieo
Abstract
values of 40.3, 39.1, and 15.1 μM, respectively. In addition, molecular docking simulations of α-glucosidase inhibition of the active compounds were studied.
Topics & Concepts
PhytochemicalCytotoxicityChemistryCircular dichroismIC50StereochemistryTraditional medicineIn vitroBiochemistryMedicineBioactive natural compoundsNatural product bioactivities and synthesisPlant chemical constituents analysis