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Chlorpromazine, an antipsychotic agent, induces G2/M phase arrest and apoptosis via regulation of the PI3K/AKT/mTOR-mediated autophagy pathways in human oral cancer

An-Jie Jhou, Hao-Chiun Chang, Chih‐Chang Hung, Han-Chen Lin, Yi‐Chen Lee, Wangta Liu, Kuang-Fen Han, Yu‐Wei Lai, Mei-Ying Lin, Chien‐Hsing Lee

2020Biochemical Pharmacology66 citationsDOI

Topics & Concepts

AutophagyPI3K/AKT/mTOR pathwayProtein kinase BApoptosisCancer researchPharmacologyChemistryCancerProgrammed cell deathCancer cellBiologyMedicineInternal medicineBiochemistryAutophagy in Disease and TherapyCannabis and Cannabinoid ResearchPolyamine Metabolism and Applications
Chlorpromazine, an antipsychotic agent, induces G2/M phase arrest and apoptosis via regulation of the PI3K/AKT/mTOR-mediated autophagy pathways in human oral cancer | Litcius