TPGS2k-PLGA composite nanoparticles by depleting lipid rafts in colon cancer cells for overcoming drug resistance
Bin Du, Wanying Zhu, Lili Yu, Yuehua Wang, Mei Zheng, Jingshu Huang, Guopeng Shen, Jie Zhou, Hanchun Yao
Topics & Concepts
Lipid raftPLGADrug deliveryDoxorubicinChemistryEffluxDrugCancer cellApoptosisIntracellularSimvastatinPharmacologyCellCell biologyCancerBiochemistryBiologyIn vitroChemotherapyOrganic chemistryGeneticsLipid Membrane Structure and BehaviorNanoparticle-Based Drug DeliveryRNA Interference and Gene Delivery