A covalent organic framework-based nanoreactor for enhanced photothermal therapy <i>via</i> inhibiting intracellular heat defense systems
Yanan Li, Jing-Jing Wan, Wenyan Li, Qun Guan, Yu‐Bin Dong
Abstract
a stepwise post-synthetic modification. The obtained GOx@COF-ICG can achieve synergistic inhibition of intracellular heat defense systems through starvation therapy to enhance photothermal therapy of tumors.
Topics & Concepts
Photothermal therapyNanoreactorGlucose oxidaseIndocyanine greenIntracellularNanotechnologyCovalent bondNanoscopic scaleChemistryBiophysicsNanomaterialsMaterials scienceNanoparticleBiochemistryBiosensorOrganic chemistryMedicineBiologySurgeryNanoplatforms for cancer theranosticsCovalent Organic Framework ApplicationsMetal-Organic Frameworks: Synthesis and Applications