Indium‐Catalyzed Deoxygenation of Sulfoxides with Hydrosilanes
Norio Sakai, Retsu Shimada, Yohei Ogiwara
Abstract
Abstract Described herein is that a novel InBr 3 /PhSiH 3 reducing system in a 1,4‐dioxane solution smoothly and effectively undertook deoxygenation of a variety of sulfoxides leading to the facile preparation of sulfide derivatives. Also, it was demonstrated that the reducing system shows a higher reactivity towards sulfoxides than that towards commonly reducible functional groups, such as carboxylic acids, esters, amides, and sulfones.
Topics & Concepts
DeoxygenationChemistryCatalysisSulfideIndiumReactivity (psychology)SulfoxideOrganic chemistrySulfurCombinatorial chemistryAlternative medicineMedicinePathologySulfur-Based Synthesis TechniquesChemical Synthesis and ReactionsCatalytic C–H Functionalization Methods