Rigid monoclonal antibodies improve detection of SARS-CoV-2 nucleocapsid protein
Curtis D. Hodge, Daniel J. Rosenberg, Patricia Grob, Mateusz Wilamowski, A. Joachimiak, Greg L. Hura, Michal Hammel
Abstract
detection sensitivity. These enhancements can expedite the development of more sensitive and selective antigen-detecting point-of-care lateral flow devices, which are critical for early diagnosis and epidemiological studies of SARS-CoV-2 and other pathogens.
Topics & Concepts
Monoclonal antibodyEpitopeAntigenEpitope mappingVirologyChemistryAntibodyMolecular biologyBiologyImmunologySARS-CoV-2 detection and testingBiosensors and Analytical DetectionSARS-CoV-2 and COVID-19 Research