Risk and protective factors for SARS-CoV-2 reinfections, surveillance data, Italy, August 2021 to March 2022
Chiara Sacco, Daniele Petrone, Martina Del Manso, Alberto Mateo‐Urdiales, Massimo Fabiani, Marco Bressi, Antonino Bella, Patrizio Pezzotti, Maria Cristina Rota, Flavia Riccardo, on behalf of the Italian Integrated Surveillance of COVID-19 study group
Abstract
We explored the risk factors associated with SARS-CoV-2 reinfections in Italy between August 2021 and March 2022. Regardless of the prevalent virus variant, being unvaccinated was the most relevant risk factor for reinfection. The risk of reinfection increased almost 18-fold following emergence of the Omicron variant compared with Delta. A severe first SARS-CoV-2 infection and age over 60 years were significant risk factors for severe reinfection.
Topics & Concepts
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)MedicineCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakRisk factorVirologyInternal medicineOutbreakInfectious disease (medical specialty)DiseaseSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesSARS-CoV-2 detection and testing