Astrocytes and microglia play orchestrated roles and respect phagocytic territories during neuronal corpse removal in vivo
Eyiyemisi C. Damisah, Robert Hill, Anupama Rai, Fuyi Chen, Carla V. Rothlin, Sourav Ghosh, Jaime Grutzendler
Abstract
. In aging, there was a marked delay in apoptotic cell removal. Thus, a precisely orchestrated response and cross-talk between glial cells during corpse removal may be critical for maintaining brain homeostasis.
Topics & Concepts
MicrogliaIn vivoNeuroscienceAstrocytePhagocytosisNeurogliaBiologyCell biologyImmunologyCentral nervous systemInflammationBiotechnologyNeuroinflammation and Neurodegeneration MechanismsImmune cells in cancerNeuroscience and Neuropharmacology Research