Diallyl trisulfide ameliorates bone loss and alters specific gut microbiota and serum metabolites in natural aging mice
Feng Zhang, Jia Xu, Yanzhou Hu, Jing‐Jing Fang, Minglan Yang, Kunlun Huang, Wentao Xu, Xiaoyun He
Abstract
gene expression levels increased in bones, which may be related to the ameliorative mechanism of DATS. Our results suggested that DATS may prevent age-related bone loss by upregulating osteogenic gene expression through altering gut microbes and serum metabolism.
Topics & Concepts
Diallyl trisulfideBone remodelingChemistryMicrobiomeGut floraBiochemistryBiologyEndocrinologyBioinformaticsApoptosisInflammatory Bowel DiseaseCancer, Lipids, and MetabolismPharmacological Effects of Medicinal Plants