Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity
Kenji Ichiyama, Jia Long, Yusuke Kobayashi, Yuji Horita, Takeshi Kinoshita, Yamami Nakamura, Chizuko Kominami, Katia Georgopoulos, Shimon Sakaguchi
Topics & Concepts
FOXP3BiologyAutoimmunityImmunologyTranscription factorChromatinPsychological repressionChromatin remodelingCancer researchImmune systemCell biologyGeneGeneticsGene expressionImmune Cell Function and InteractionT-cell and B-cell ImmunologyImmunotherapy and Immune Responses