Synthesis, in vitro urease inhibitory potential and molecular docking study of bis-indole bearing sulfonamide analogues
Hayat Ullah, Ghazala Arshad, Fazal Rahim, Ayesha Nawaz, Fahad Khan, Naveed Iqbal, Shawkat Hayat, Hussan Zada, Abdus Samad, Abdul Wadood
Topics & Concepts
ChemistryIndole testStereochemistryThioureaDocking (animal)SubstituentSulfonamideIC50EnzymeUreaseActive siteIn vitroCombinatorial chemistryBiochemistryOrganic chemistryNursingMedicineEnzyme function and inhibitionCholinesterase and Neurodegenerative DiseasesSynthesis and biological activity