Comparative Genomic Analysis Provides Insights into the Evolution and Genetic Diversity of Community-Genotype Sequence Type 72 Staphylococcus aureus Isolates
Wangxiao Zhou, Ye Jin, Yanzi Zhou, Yuan Wang, Luying Xiong, Qixia Luo, Yonghong Xiao
Abstract
Understanding the evolution and dissemination of community-genotype ST72 Staphylococcus aureus isolates is important, as isolates of this lineage have rapidly spread into hospital settings and caused serious health issues. In this study, we first carried out genome-wide analysis of 107 global ST72 isolates to characterize the evolution and genetic diversity of the ST72 lineage.
Topics & Concepts
BiologyMultilocus sequence typingCladeVirulenceMobile genetic elementsGenotypePhylogenetic treeLineage (genetic)Staphylococcus aureusSCCmecAntibiotic resistanceGenetic diversityGeneticsGenomeWhole genome sequencingSequence analysisMethicillin-resistant Staphylococcus aureusGeneAntibioticsPopulationBacteriaMedicineEnvironmental healthAntimicrobial Resistance in StaphylococcusBacterial biofilms and quorum sensingBiochemical and Structural Characterization