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The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis

Runbin Sun, Bo Kong, Na Yang, Bei Cao, Dong Feng, Xiaoyi Yu, Chun Ge, Siqi Feng, Fei Fei, Jingqiu Huang, Zhenyao Lu, Yuan Xie, Chung S. Yang, Grace L. Guo, Guangji Wang, Jiye Aa

2020Drug Metabolism and Disposition47 citationsDOIOpen Access PDF

Topics & Concepts

GluconeogenesisFarnesoid X receptorPhosphoenolpyruvate carboxykinaseEndocrinologyInternal medicineBerberineChemistryBile acidMetaboliteBiochemistryMetabolismPharmacologyBiologyEnzymeNuclear receptorGeneMedicineTranscription factorBerberine and alkaloids researchDrug Transport and Resistance MechanismsGinseng Biological Effects and Applications
The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis | Litcius