<i>Streptococcus mutans</i> PrsA mediates AtlA secretion contributing to extracellular DNA release and biofilm formation in the pathogenesis of infective endocarditis
Chih-Chieh Hsu, Ron‐Bin Hsu, Xoong-Harng Oon, Ya-Tang Chen, Jeng‐Wei Chen, Che-Hao Hsu, Yu‐Min Kuo, Yi‐Hsien Shih, Jean‐San Chia, Chiau‐Jing Jung
Abstract
PrsA could regulate AtlA-mediated eDNA release to contribute to biofilm formation in the pathogenesis of IE.
Topics & Concepts
BiofilmMicrobiologyVirulencePathogenesisBiologySecretionComplementationStreptococcus mutansStreptococcus gordoniiFoldaseMutantBacteriaGroELImmunologyBiochemistryGeneGeneticsEscherichia coliStreptococcal Infections and TreatmentsAntimicrobial Resistance in StaphylococcusInfective Endocarditis Diagnosis and Management