IL-17RA-signaling in Lgr5+ intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment
Xun Lin, Stephen Gaudino, Kyung Ku Jang, Tej Bahadur, Ankita Singh, Anirban Banerjee, Michael Beaupre, Timothy Chu, Hoi Tong Wong, Chang-Kyung Kim, Cody Kempen, Jordan E. Axelrad, Huakang Huang, Saba Khalid, Vyom Shah, Onur Eskiocak, Olivia B. Parks, Artan Berisha, Jeremy P. McAleer, Misty Good, Miko Hoshino, Richard S. Blumberg, Agnieszka B. Bialkowska, Sarah L. Gaffen, Jay K. Kolls, Vincent W. Yang, Semir Beyaz, Ken Cadwell, Pawan Kumar
Topics & Concepts
LGR5BiologyCell biologyStem cellTranscription factorCellular differentiationCytokineImmunologyEnteroendocrine cellPaneth cellCancer stem cellEndocrinologySmall intestineGeneticsGeneEndocrine systemHormoneDigestive system and related healthIL-33, ST2, and ILC PathwaysCancer Cells and Metastasis