Idiopathic inflammatory myopathies: one year in review 2022
Eduardo Dourado, Francesca Bottazzi, Chiara Cardelli, Edoardo Conticini, Jens Schmidt, Lorenzo Cavagna, Simone Barsotti
Abstract
Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of disorders in which chronic inflammation of the skeletal muscle, leading to muscle weakness, is a common feature. Different phenotypes have been identified within the IIM spectrum based on extra-muscular manifestations, immunology, muscle histology, responsiveness to therapy, and prognosis. The pathogenesis, classification, treatment, and prognosis of the different IIM subtypes are subject to active discussion and research. This review highlights the most relevant literature published on this topic over the last year.
Topics & Concepts
MedicinePathogenesisInflammationSkeletal muscleMyositisMuscle weaknessMuscle diseaseWeaknessPathologyImmunologyInternal medicineDiseaseSurgeryInflammatory Myopathies and DermatomyositisPeripheral Neuropathies and DisordersImmunodeficiency and Autoimmune Disorders