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Electrochemical Gold‐Catalyzed 1,2‐Difunctionalization of C−C Multiple Bonds**

Anil Kumar, Khyati Shukla, Salman Ahsan, Amit Paul, Nitin T. Patil

2023Angewandte Chemie International Edition27 citationsDOIOpen Access PDF

Abstract

Abstract Herein, we disclose the first report of 1,2‐difunctionalization of C−C multiple bonds using electrochemical gold redox catalysis. By adopting the electrochemical strategy, the inherent π‐activation and cross‐coupling reactivity of gold catalysis are harnessed to develop the oxy‐alkynylation of allenoates under external‐oxidant‐free conditions. Detailed mechanistic investigations such as 31 P NMR, control experiments, mass studies, and cyclic voltammetric (CV) analysis have been performed to support the proposed reaction mechanism.

Topics & Concepts

ElectrochemistryReactivity (psychology)CatalysisChemistryRedoxCombinatorial chemistryCoupling reactionReaction mechanismAlkynylationInorganic chemistryOrganic chemistryPhysical chemistryElectrodeMedicinePathologyAlternative medicineCatalytic C–H Functionalization MethodsCatalytic Alkyne ReactionsSulfur-Based Synthesis Techniques
Electrochemical Gold‐Catalyzed 1,2‐Difunctionalization of C−C Multiple Bonds** | Litcius