Comparison of 18F-FDG, 68Ga-FAPI, and 68Ga-DOTATATE PET/CT in a Patient With Pancreatic Neuroendocrine Tumor
Zhaoting Cheng, Sijuan Zou, Siyuan Cheng, Shuang Song, Xiaohua Zhu
Abstract
ABSTRACT: We present image findings of 18F-FDG, 68Ga-FAPI, and 68Ga-DOTATATE PET/CT in a 35-year-old woman with multiple metastases of pancreatic neuroendocrine tumor. The images of PET/CTs using 3 different tracers all showed multiple foci of increased activities in the liver and pancreas body, in which 68Ga-FAPI PET/CT displayed the highest tumor-to-liver ratios. However, 68Ga-DOTATATE PET/CT detected more small metastatic lymph node and bone metastases, which were missed by both FDG and FAPI PET/CT.
Topics & Concepts
MedicinePancreasLymph nodeNuclear medicinePET-CTNeuroendocrine tumorsRadiologyPositron emission tomographyPathologyInternal medicinePeptidase Inhibition and AnalysisCardiac Structural Anomalies and RepairNeuropeptides and Animal Physiology