Synthesis and evaluation of 3,4,5-trisubstituted triazoles as G protein-biased kappa opioid receptor agonists
Ashley E Trojniak, Vuong Q Dang, Kerri M. Czekner, Robin J Russo, Lilyan M Mather, Edward L. Stahl, Michael D. Cameron, Laura Bohn, Jeffrey Aubé
Topics & Concepts
Chemistryκ-opioid receptorKappaOpioidReceptorOpioid receptorStereochemistryPharmacologyBiochemistryLinguisticsPhilosophyMedicineReceptor Mechanisms and SignalingNeuropeptides and Animal PhysiologyComputational Drug Discovery Methods