Fuzhuan brick tea ameliorates hepatic steatosis and steatohepatitis through gut microbiota-derived aryl hydrocarbon receptor ligands in high-fat diet-induced obese mice
Dongmin Liu, Siyu Wang, Yaqing Liu, Yong Luo, Beibei Wen, Wenliang Wu, Hongliang Zeng, Jianan Huang, Zhonghua Liu
Abstract
High-fat diet (HFD) induced hepatic steatosis and steatohepatitis were ameliorated by Fuzhuan brick tea (FBT) via AhR-ligand producing microbiota and their tryptophan metabolism.
Topics & Concepts
SteatohepatitisSteatosisAryl hydrocarbon receptorFatty liverInternal medicineGut floraDysbiosisEndocrinologyBiologyMedicineImmunologyBiochemistryTranscription factorDiseaseGeneTryptophan and brain disordersGut microbiota and healthTea Polyphenols and Effects