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Affinity-coupled CCL22 promotes positive selection in germinal centres

Bo Liu, Yihan Lin, Jiacong Yan, Jiacheng Yao, Dan Liu, Weiwei Ma, Jianbin Wang, Wanli Liu, Chengshuo Wang, Luo Zhang, Hai Qi

2021Nature69 citationsDOI

Topics & Concepts

Germinal centerCCL17CD40ChemokineCXCL13B cellCCL22Naive B cellCell biologySomatic hypermutationAffinity maturationChemistryChemokine receptorAntibodyMolecular biologyBiologyReceptorImmunologyCytotoxic T cellIn vitroBiochemistryT-cell and B-cell ImmunologyImmunotherapy and Immune ResponsesImmune Cell Function and Interaction
Affinity-coupled CCL22 promotes positive selection in germinal centres | Litcius